发明名称 |
Methods Of Propagating Rhinovirus C In Previously Unsusceptible Cell Lines |
摘要 |
The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided. |
申请公布号 |
US2017082609(A1) |
申请公布日期 |
2017.03.23 |
申请号 |
US201514836327 |
申请日期 |
2015.08.26 |
申请人 |
Wisconsin Alumni Research Foundation |
发明人 |
Gern James E.;Bochkov Yury A.;Palmenberg Ann C. |
分类号 |
G01N33/50;C12N7/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
1. A method of propagating rhinovirus C or rhinovirus C variant, the method comprising the steps of:
a. obtaining a host cell comprising at least one heterologous CDHR3 receptor; and b. infecting the host cell with a sample of rhinovirus C or rhinovirus C variant; wherein the rhinovirus C propagates. |
地址 |
Madison WI US |