发明名称 Methods Of Propagating Rhinovirus C In Previously Unsusceptible Cell Lines
摘要 The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
申请公布号 US2017082609(A1) 申请公布日期 2017.03.23
申请号 US201514836327 申请日期 2015.08.26
申请人 Wisconsin Alumni Research Foundation 发明人 Gern James E.;Bochkov Yury A.;Palmenberg Ann C.
分类号 G01N33/50;C12N7/00 主分类号 G01N33/50
代理机构 代理人
主权项 1. A method of propagating rhinovirus C or rhinovirus C variant, the method comprising the steps of: a. obtaining a host cell comprising at least one heterologous CDHR3 receptor; and b. infecting the host cell with a sample of rhinovirus C or rhinovirus C variant; wherein the rhinovirus C propagates.
地址 Madison WI US