| 发明名称 |
POLYMORPHISMS IN THE PDE3A GENE |
| 摘要 |
Embodiments of the invention are directed to identifying or treating a patient that would benefit from phosphodiesterase inhibitor therapy. |
| 申请公布号 |
US2017081722(A1) |
申请公布日期 |
2017.03.23 |
| 申请号 |
US201615369569 |
申请日期 |
2016.12.05 |
| 申请人 |
The Regents of the University of Colorado, a Body Corporate |
发明人 |
Sucharov Carmen;Bristow Michael;Taylor Matthew;Slavov Dobromir |
| 分类号 |
C12Q1/68;A61K31/4166 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating a patient with heart failure comprising treating the patient with an effective amount of a PDE3A inhibitor after the patient is determined to be homozygous for an ectotropic viral integration site-1 protein (Evi-1) insertional polymorphism in the promoter of the phosphodiesterase type 3A (PDE3A) gene. |
| 地址 |
Denver CO US |
