发明名称 |
THE EXOCYST AS A NOVEL DRUG TARGET OF ENDOSIDIN2 AND APPLICATION AS A THERAPEUTIC |
摘要 |
A method of altering exocytosis in a plant or animal cell is provided. The method includes exposing the cell to a compound that binds to an EXO70 protein isoform. Also provided is a method of treating diabetes or cancer in a subject in need thereof, which includes administering to the subject an effective amount of a compound that binds to an EXO70 protein isoform. In addition, a method of screening for a substance that alters exocytosis in a plant or animal cell is provided, and analogs of compound Endosidin2 are also provided. |
申请公布号 |
WO2017049016(A1) |
申请公布日期 |
2017.03.23 |
申请号 |
WO2016US52020 |
申请日期 |
2016.09.15 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
RAIKHEL, Natasha, V.;HICKS, Glenn, R.;ZHANG, Chunhua |
分类号 |
C40B30/04;A61K38/17;A61P3/10;A61P35/00;G01N33/50 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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