| 发明名称 |
KERATIN 17 AS A BIOMARKER FOR HEAD AND NECK CANCERS |
| 摘要 |
The current disclosure provides methods for detecting and analyzing KRT17 expression in a sample obtained from a subject. The current disclosure also pertains to methods and kits for identifying a mammalian subject with head and neck squamous cell carcinoma. The current disclosure further provides methods and kits for determining the likelihood of survival of a subject having head and neck squamous cell carcinoma. |
| 申请公布号 |
US2017082632(A1) |
申请公布日期 |
2017.03.23 |
| 申请号 |
US201515311611 |
申请日期 |
2015.05.15 |
| 申请人 |
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK |
发明人 |
SHROYER Kenneth;MO Michelle;SHROYER Annie |
| 分类号 |
G01N33/574 |
主分类号 |
G01N33/574 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of diagnosing a mammalian subject with head and neck squamous cell carcinoma (HNSCC) comprising
(a) obtaining a sample from said subject; and (b) detecting the level of KRT17 expression in said sample, wherein said detecting comprises contacting said sample with an mouse monoclonal antibody that binds KRT17 protein and determining the level of KRT17 bound to said mouse monoclonal antibody, and wherein KRT17 expression in at least 5% of cells in said sample indicates the presence of HSNCC in said subject. |
| 地址 |
Albany NY US |
