发明名称 DNA BINDING AGENTS WITH A MINOR GROOVE BINDING TAIL
摘要 Provided herein are compounds which intercalate into the DNA of a cell and are capable of crossing the blood brain barrier of a formula provided herein. Pharmaceutical compositions of the compounds and methods of treating cancer, for example brain, lung, or pancreatic cancer, are also provided herein.
申请公布号 WO2017049091(A1) 申请公布日期 2017.03.23
申请号 WO2016US52144 申请日期 2016.09.16
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 PRIEBE, Waldemar;GUO, Liwei;KAZIMIERSKI, Arkadiusz;FOKT, Izabela;MADDEN, Timothy;CONRAD, Charles
分类号 C07C13/66;C07C15/38;C07D309/10;C07D309/14 主分类号 C07C13/66
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