发明名称 |
DNA BINDING AGENTS WITH A MINOR GROOVE BINDING TAIL |
摘要 |
Provided herein are compounds which intercalate into the DNA of a cell and are capable of crossing the blood brain barrier of a formula provided herein. Pharmaceutical compositions of the compounds and methods of treating cancer, for example brain, lung, or pancreatic cancer, are also provided herein. |
申请公布号 |
WO2017049091(A1) |
申请公布日期 |
2017.03.23 |
申请号 |
WO2016US52144 |
申请日期 |
2016.09.16 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
PRIEBE, Waldemar;GUO, Liwei;KAZIMIERSKI, Arkadiusz;FOKT, Izabela;MADDEN, Timothy;CONRAD, Charles |
分类号 |
C07C13/66;C07C15/38;C07D309/10;C07D309/14 |
主分类号 |
C07C13/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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