发明名称 |
IMMUNE ADJUSTMENT COMPOUND, USE THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME |
摘要 |
The present invention provides a compound represented by formula I, wherein R is a halogen element or a C1-C6 alkyl group. The compound has S1 P1 receptor agonist activity and selective specificity and has obviously-shortened half-life in-vivo, and therefore the compound is a high-quality second-generation S1P1 receptor agonist. The present invention also provides a use of the compound in preparing medicine for treating diseases or symptoms mediated by an S1P1 receptor, a pharmaceutical composition comprising the compound, and uses of the compound and the pharmaceutical composition in treating diseases or symptoms mediated by the S1 P1 receptor. |
申请公布号 |
EP3048103(A4) |
申请公布日期 |
2017.03.22 |
申请号 |
EP20140846294 |
申请日期 |
2014.09.15 |
申请人 |
SUZHOU CONNECT BIOPHARMACEUTICALS, LTD. |
发明人 |
ZHENG, Wei;PAN, Wubin;YANG, Xin |
分类号 |
C07D413/10;A61K31/4245;A61P1/00;A61P1/04;A61P3/10;A61P9/10;A61P11/06;A61P17/06;A61P19/02;A61P19/04;A61P25/00;A61P29/00;A61P31/12;A61P35/00;A61P37/02;A61P37/06 |
主分类号 |
C07D413/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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