发明名称 |
HETEROCYCLIC HYDROXAMIC ACIDS AS PROTEIN DEACETYLASE INHIBITORS AND DUAL PROTEIN DEACETYLASE-PROTEIN KINASE INHIBITORS AND METHODS OF USE THEREOF |
摘要 |
The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mps1 kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mps1 kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation. |
申请公布号 |
EP3142652(A1) |
申请公布日期 |
2017.03.22 |
申请号 |
EP20150792349 |
申请日期 |
2015.05.14 |
申请人 |
The Regents of the University of Colorado, a body corporate |
发明人 |
LIU, Xuedong;ZHANG, Gan;CHAN, Daniel, Chuen-Fong;PISCOPIO, Anthony, D. |
分类号 |
A61K31/165 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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