| 发明名称 |
PYRROLO PYRIMIDINE DERIVATIVE |
| 摘要 |
The compound represented by general formula (I) has strong Axl inhibition activity by means of a pyridone ring structure being introduced into a pyrrolo pyrimidine skeleton, and so the result can serve as a treatment agent for Axl-related diseases, for example cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glial tumors, renal disease, immune system disorders, and cardiovascular disease. |
| 申请公布号 |
EP3067356(A4) |
申请公布日期 |
2017.03.22 |
| 申请号 |
EP20140859491 |
申请日期 |
2014.11.06 |
| 申请人 |
ONO Pharmaceutical Co., Ltd. |
发明人 |
INUKAI, Takayuki;TAKEUCHI, Jun;YASUHIRO, Tomoko;WOLF, Mark Allan;PAWAR, Vijay Dattaram;CHAKRABARTI, Anjan;CHITTIMALLA, Santhosh Kumar |
| 分类号 |
C07D487/04;A61K31/519;A61P9/00;A61P13/12;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P43/00 |
主分类号 |
C07D487/04 |
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