| 摘要 |
A microfluidic active matrix electro wetting on dielectric device (AM-EWOD) and a method of filling such a device, wherein the device comprises a chamber 109 having one or more inlet ports 111 and is configured that when the chamber contains a metered volume of a filler fluid 107 it is partially filled and the further addition of a volume of assay fluid 108 into the chamber via one or more of the inlet ports results in the displacement a volume of a venting fluid to vent from the chamber. The venting fluid may be air and the device may comprise a venting channel 115. The assay fluid within the chamber may be controlled by the actuation of electrodes. Alternatively, the chamber is completely filled with filler fluid and when assay fluid is added a sufficient amount of filler fluid is extracted. |
