| 发明名称 | Cell penetrating peptides for intracellular delivery of molecules | ||
| 摘要 | A cell-penetrating peptide characterized in that it comprises an amino acid sequence: X1X2X3WWX4X5WAX6X3X7X8X9X10X11X12WX13R (SEQ ID No: 10), wherein X1, is beta-A or S, X2 is L or none, X3 is R or none, X4 is L, R or G, X5 is R, W or S, X6 is S, P or T, X7 is W or P, X8 is F, A or R, X9 is S, L, P or R, X10 is R or S, X11 n is W or none, X12 is A, R or none and X13 is W or F, and wherein if X3 is none, then X3, X11 and X12 are none as well. | ||
| 申请公布号 | US9598465(B2) | 申请公布日期 | 2017.03.21 |
| 申请号 | US201314433573 | 申请日期 | 2013.10.04 |
| 申请人 | AADIGEN LLC | 发明人 | Divita Gilles;Deshayes Sebastien;Konate Karidia;Morris May Catherine |
| 分类号 | A61K47/42;A61K47/48;C07K7/08;C07K14/00;A61K9/51;A61K38/00 | 主分类号 | A61K47/42 |
| 代理机构 | Morrison & Foerster LLP | 代理人 | Morrison & Foerster LLP |
| 主权项 | 1. A cell-penetrating peptide characterized in that it comprises an amino acid sequence: X1X2X3WWX4X5WAX6X3X7X8X9X10X11X12WX13R (SEQ ID No: 10), wherein X1 is beta-A or S, X2 is L or none, X3 is R or none, X4 is L, R or G, X5 is R, W or S, X6 is S, P or T, X7 is W or P, X8 is F, A or R, X9 is S, L, P or R, X10 is R or S, X11 is W or none, X12 is A, R or none and X13 is W or F, and wherein if X3 is none, then X2, X11 and X12 are none as well. | ||
| 地址 | Pacific Palisades CA US | ||