Bis-organometallic 2-amino-3-hydroxy-2-methylpropanenitrile derivatives for use as anthelmintics

摘要

The invention comprises a compound characterized by a general formula (1),;;wherein X is a group described by a general formula —Kp—Fl—Kq—, wherein
Fl is —C(═O)—, —C(═S)—, with l being 0 or 1,Kp is a Cp-alkyl with p being 0, 1, 2, 3 or 4,Kq is a Cq-alkyl with q being 0, 1, 2, 3 or 4, and;wherein Z is a group described by a general formula —Kr—Fi—Kt—, wherein
Fi —O—, —S—, —O—C(═O)—, —O—C(═S)—, —S—C(═O)— or —NH—(C═O)— with i being 0 or 1,Kr is a Cr-alkyl with r being 0, 1, 2, 3 or 4,Kt is a Ct-alkyl with t being 0, 1, 2, 3 or 4,;wherein each OM is an organometallic compound independently selected from each other from the group of an unsubstituted or substituted metal sandwich compound, an unsubstituted or substituted half metal sandwich compound or a metal carbonyl compound and their use.

主权项

1. A compound characterized by a general formula (1), wherein X is a group described by a general formula —Kp—Fl—Kq—, wherein
Fl is —C(═O)—, —C(═S)—, with l being 0 or 1,Kp is a Cp-alkyl with p being 0, 1, 2, 3 or 4,Kq is a Cq-alkyl with q being 0, 1, 2, 3 or 4, and wherein Z is a group described by a general formula —Kl—Fl—Kt—, wherein
Fl is —O—, —S—, —O—C(═O)—, —O—C(═S)—, —S—C(═O)— or —NH—(C═O)— with i being 0 or 1,Kr is a Cr-alkyl with r being 0, 1, 2, 3 or 4,Kt is a Ct-alkyl with t being 0, 1, 2, 3 or 4, wherein each OM is an organometallic compound independently selected from each other from the group of an unsubstituted or substituted metal sandwich compound, an unsubstituted or substituted half metal sandwich compound or a metal carbonyl compound.