Lipoprotein lipase for treatment of hypertriglyceridemic-related conditions including acute pancreatitis

摘要

A lipoprotein lipase (LPL) protein for treating and/or preventing HTG and its associated diseases, including but not limited to acute pancreatitis (AP), and in particular, acute pancreatitis secondary to or exacerbated by hypertriglyceridemia, and hypertriglyceridemia and its associated diseases in general, including cardiovascular and metabolic diseases, endocrine disorders, and fat embolism syndrome.

主权项

1. A method of treating hypertriglyceridemia comprising administering a LPL polypeptide to a subject in need of treatment, wherein the LPL polypeptide comprises or consists of the amino acid of SEQ ID NO: 2.