| 发明名称 | Liquid oral simvastatin compositions | ||
| 摘要 | A suspension which is suitable for oral administration, comprising simvastatin, at least one suspending agent, and at least one preservative, wherein at least 90 wt % of the particles of simvastatin are less than 100 μm in diameter. The present invention also includes uses of the suspension and methods of making the suspension. | ||
| 申请公布号 | US9597289(B2) | 申请公布日期 | 2017.03.21 |
| 申请号 | US200712298451 | 申请日期 | 2007.04.26 |
| 申请人 | ROSEMONT PHARMACEUTICALS LTD. | 发明人 | Driver Phillip |
| 分类号 | A61K9/10;A61K31/22;A61K9/00;A61K31/351;A61P3/06;A61K31/366 | 主分类号 | A61K9/10 |
| 代理机构 | Thompson Hine LLP | 代理人 | Thompson Hine LLP |
| 主权项 | 1. An aqueous suspension which is suitable for oral administration, wherein 5 ml of suspension comprises:AmountConstituent(mg/5 ml)Purified WaterQ.S.Magnesium Aluminium silicate20Propylene glycol75Methyl hydroxybenzoate8Ethyl hydroxybenzoate2Propyl hydroxybenzoate0.8Carmellose sodium10Simethicone1Citric Acid Monohydrate3.75Disodium Hydrogen Phosphate anhydrous11.25Sodium Lauryl sulphate0.05Simvastatin having d90 ≦ 20 μm20. | ||
| 地址 | Leeds GB | ||