Magnetic and fluorescent reverse nanoassemblies

摘要

The present invention relates to magnetic and fluorescent nanoassemblies having reverse architectures. Especially, the nanoassemblies of the invention comprise a fluorescent core and magnetic nanoparticles contacting the surface of the fluorescent core. The nanoassemblies of the invention may further be coated by a polymer, which may optionally be functionalized. The invention further relates to a process for manufacturing the nanoassemblies of the invention. The invention is also directed to the use of the nanoassemblies of the invention, especially for multimodal imaging, in vitro and/or in vivo diagnostics through multimodal imaging, and/or therapy.

主权项

1. A nanoassembly comprising:
one single fluorescent core comprising fluorescent organic molecules, and magnetic nanoparticles contacting the surface of said fluorescent core; wherein the fluorescent core does not comprise a polymer or silica; and wherein the nanoassembly has a hydrodynamic diameter ranging from 20 to 800 nm.