| 发明名称 |
CONVERSION OF THEBAINE TO MORPHINE DERIVATIVES |
| 摘要 |
The present invention provides methods for the conversion of the thebaine to a morphine derivative, such as hydrocodone. Novel ketal intermediates fo the conversion are provided. A one-pot procedure for the conversion comprises treating thebaine with an acid in the presence of a metal catalyst. |
| 申请公布号 |
CA2692429(C) |
申请公布日期 |
2017.03.21 |
| 申请号 |
CA20082692429 |
申请日期 |
2008.06.30 |
| 申请人 |
BROCK UNIVERSITY |
发明人 |
COX, D. PHILLIP;CARROLL, ROBERT JAMES;HUDLICKY, TOMAS;LEISCH, HANNES |
| 分类号 |
C07D489/02;C07D489/04 |
主分类号 |
C07D489/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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