| 发明名称 |
VASCULAR ENDOTHELIAL CELL GROWTH FACTOR VARIANTS AND USES THEREOF |
| 摘要 |
The present invention provides VEGF variants having at least a single amino acid mutation in the native VEGF sequence and selective binding affinity for either the KDR receptor or the FLT-1 receptor. Methods of making the VEGF variants and methods of using the VEGF variants are also provided. |
| 申请公布号 |
CA2370246(C) |
申请公布日期 |
2017.03.21 |
| 申请号 |
CA20002370246 |
申请日期 |
2000.04.10 |
| 申请人 |
GENENTECH, INC. |
发明人 |
CUNNINGHAM, BRIAN;DEVOS, ABRAHAM;LI, BING |
| 分类号 |
C12N15/12;G01N33/68;A61K38/00;A61K38/18;A61P9/00;A61P43/00;C07K14/515;C07K14/52;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;G01N33/566 |
主分类号 |
C12N15/12 |
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