| 发明名称 |
Peptides and their use in the treatment of skin |
| 摘要 |
Peptides (and derivatives thereof), topical compositions, and methods of diminishing signs of aging and/or improving health of human integuments are provided. The peptides are derived from human Growth Differentiation Factor 11 (GDF-11). |
| 申请公布号 |
US9597274(B2) |
申请公布日期 |
2017.03.21 |
| 申请号 |
US201514742060 |
申请日期 |
2015.06.17 |
| 申请人 |
Avon Products, Inc. |
发明人 |
Idkowiak-Baldys Jolanta;Lyga John W.;Santhanam Uma |
| 分类号 |
A61K38/04;C07K7/00;A61K8/64;A61Q19/08;A61K8/365;A61K8/36;A61K8/49 |
主分类号 |
A61K38/04 |
| 代理机构 |
|
代理人 |
McCloskey Brian P. |
| 主权项 |
1. A method for diminishing the appearance of dermatological signs of aging comprising topically applying to the skin in need thereof a composition comprising, in a topically acceptable vehicle, an active agent comprising a GDF-11 peptide fragment consisting of the sequence LRLK (SEQ ID NO: 453), MVV (SEQ ID NO: 369), or QILSKLRL (SEQ ID NO: 2028), and/or C1-24 aliphatic derivatives thereof. |
| 地址 |
Rye NY US |
