Methods and compositions for treating dry eye disease and other eye disorders

摘要

The present invention discloses pharmaceutical preparations for treatment of eye disorders containing an alpha 2 adrenergic agonist, to processes for producing the pharmaceutical preparations and methods for treatment of various eye disorders including dry eye and Meibomian gland dysfunction and a medicinal applicator for topical application of an alpha 2 adrenergic agonist to a subject, a package assembly for the medicinal applicator and methods of using the medicinal applicator to treat eye disorders.

主权项

1. A method of treating a patient suffering from a dry eye syndrome comprising administering to an eye of the patient in need of such a treatment an ophthalmological pharmaceutical formulation comprising nanoemulsion of oil, a therapeutically effective amount of an active ingredient for treating a dry eye syndrome, wherein said active ingredient consists of an alpha 2 adrenergic agonist having a higher alpha 2A agonist activity compared to alpha 2B agonist activity or a pharmaceutically acceptable salt thereof.