Compositions and methods for the treatment of neurodegenerative and other diseases

摘要

In one embodiment, the present application discloses methods of treating diseases and disorders with sulfasalazine and pharmaceutical formulations of sulfasalazine where the bioavailability of the sulfasalazine is increased. In another embodiment, the present application also provides dosing regimens for treating neurodegenerative diseases and disorders with compositions comprising sulfasalazine.

主权项

1. A pharmaceutical composition comprising a solid dispersion of:
sulfasalazine, in essentially amorphous form, and PVP VA64, having a ratio of sulfasalazine to PVP VA64 between about 20:80 wt./wt. to 30:70 wt./wt.