发明名称 | Therapeutic compositions containing macitentan | ||
摘要 | The invention relates to a product containing the compound of formula (I) below or a pharmaceutically acceptable salt of this compound, in combination with at least one compound having prostacyclin receptor (IP) agonist properties, or a pharmaceutically acceptable salt thereof.; | ||
申请公布号 | US9597331(B2) | 申请公布日期 | 2017.03.21 |
申请号 | US201514873787 | 申请日期 | 2015.10.02 |
申请人 | ACTELION PHARMACEUTICALS LTD. | 发明人 | Clozel Martine |
分类号 | A61K31/506;A61K31/5578;A61K31/343;A61K31/4965;A61K31/5575;A61K45/06 | 主分类号 | A61K31/506 |
代理机构 | Hoxie & Associates LLC | 代理人 | Hoxie & Associates LLC |
主权项 | 1. A method for the treatment of a disease selected from hypertension, pulmonary hypertension, diabetic arteriopathy, heart failure, erectile dysfunction, angina pectoris and pulmonary fibrosis, comprising administering macitentan, in free or pharmaceutically acceptable salt form, in combination with an effective amount of at least one compound having prostacyclin receptor (IP) agonist properties, or a pharmaceutically acceptable salt thereof, wherein the compound having prostacyclin receptor (IP) agonist properties is selected from iloprost and its pharmaceutically acceptable salts. | ||
地址 | Allschwil CH |