Lectina específica de L-fucosa alfa1-6

摘要

Disclosed is a novel lectin which can bind specifically to an L-fucose ±1†’6 sugar chain. Also disclosed is use of the lectin. The L-fucose ±1†’6 specific lectin of the present invention is characterized in that : (1) the lectin is extracted from a basidiomycete or an ascomycete; (2) the lectin has has a molecular weight by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of 4,000 to 40,000; and (3) the lectin has has an affinity to an L-fucose ±1†’6 sugar chain, the affinity being represented by an association constant of 1.0×10 4 M -1 or more (at 25 degrees C). The lectin can be used for detecting an L-fucose ±1†’6 sugar chain specifically, and is effective for the purification of an L-fucose ±1†’6 sugar chain or a non L-fucose ±1†’6 sugar chain.