发明名称 |
Bispecific HER2 and CD3 binding molecules |
摘要 |
Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to CD3, a T cell receptor, and mediate T cell cytotoxicity for managing and treating disorders, such as cancer. Also provided herein are uses and methods for managing and treating HER2 -related cancers. |
申请公布号 |
AU2015292374(A1) |
申请公布日期 |
2017.03.16 |
申请号 |
AU20150292374 |
申请日期 |
2015.07.24 |
申请人 |
Memorial Sloan Kettering Cancer Center |
发明人 |
Cheung, Nai-Kong V.;Lopez-Albaitero, Andres;Xu, Hong |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C07K16/32;C07K16/46 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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