发明名称 Bispecific HER2 and CD3 binding molecules
摘要 Provided herein are compositions, methods, and uses involving bispecific binding molecules that specifically bind to HER2, a receptor tyrosine kinase, and to CD3, a T cell receptor, and mediate T cell cytotoxicity for managing and treating disorders, such as cancer. Also provided herein are uses and methods for managing and treating HER2 -related cancers.
申请公布号 AU2015292374(A1) 申请公布日期 2017.03.16
申请号 AU20150292374 申请日期 2015.07.24
申请人 Memorial Sloan Kettering Cancer Center 发明人 Cheung, Nai-Kong V.;Lopez-Albaitero, Andres;Xu, Hong
分类号 C07K16/28;A61K39/395;A61P35/00;C07K16/32;C07K16/46 主分类号 C07K16/28
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