| 摘要 |
Provided herein are improved compositions comprising lactoferrin and methods for modulating T cell subtypes and their activities in a subject, to improve the balance between anti¬ inflammatory (Th2) cytokine producing cells and pro-inflammatory (Thl) or Thl7 cells, and skew naive T cells toward a pro-regulatory phenotype, for the treatment and/or amelioration of neurodegenerative or autoimmune diseases and disorders (e.g., inflammatory bowel disease (IBD), amyotrophic lateral sclerosis (ALS), Alzheimers disease, cognitive decline in the elderly resulting from chronic inflammation, and/or rheumatoid arthritis (RA)). |
