| 发明名称 |
Primary amine diazeniumdiolate heterocyclic derivatives |
| 摘要 |
A compound having the structure (I) useful for treating hypertension, Pulmonary Arterial Hypertension (PAH), congestive heart failure, conditions resulting from excessive water retention, cardiovascular disease, diabetes, oxidative stress, endothelial dysfunction, cirrhosis, pre-eclampsia, osteoporosis or nephropathy. |
| 申请公布号 |
AU2012225712(B2) |
申请公布日期 |
2017.03.16 |
| 申请号 |
AU20120225712 |
申请日期 |
2012.03.05 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Ali, Amjad;Lo, Michael Man-Chu;Whitehead, Brent;Shah, Shrenik K.;Henderson, Timothy J.;Yan, Lin;Guo, Zhiqiang |
| 分类号 |
C07D207/12;A61K31/445;C07D207/273;C07D207/48;C07D211/46;C07D211/96;C07D223/08;C07D309/12;C07D401/04;C07D401/06;C07D401/10;C07D401/14;C07D403/04;C07D403/10;C07D405/12 |
主分类号 |
C07D207/12 |
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