| 发明名称 |
Modified Natural Killer Cells and Uses Thereof |
| 摘要 |
The present invention provides, in certain aspects, a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15), and methods for producing such cells. The invention further provides methods of using a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15) to treat cancer in a subject or to enhance expansion and/or survival of NK cells. |
| 申请公布号 |
US2017073638(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201515309362 |
申请日期 |
2015.05.14 |
| 申请人 |
National University of Singapore ;St. Jude Children's Research Hospital, Inc. |
发明人 |
CAMPANA Dario;SHOOK David;IMAMURA Masaru |
| 分类号 |
C12N5/0783;C07K14/705;C07K14/54;A61K38/20;A61K35/17 |
主分类号 |
C12N5/0783 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15). |
| 地址 |
Singapore SG |
