SYNTHESIS OF DIKETONE COMPOUNDS FROM CARBOHYDRATES

摘要

Providing a catalytic process for preparing 1,4-diketone compounds from furanic compounds and their precursors in a liquid medium, using an acid catalytic system and optionally in the presence of hydrogen and a hydrogenation catalyst, wherein the acidic catalytic system comprises a solid acid catalyst or a mixture of water and CO2.

主权项

1. A process for preparing 1,4-diketone compounds from a furanic compound of structure (I) or the precursor thereof [Compound (F)] in a liquid medium, wherein: in structure (I), n is an integer between 0 and 4, and each R, being same or different, is independently selected from a group consisting of: hydrogen, —OH, —CHO, halogen, alkyl, alkenyl, alkynyl, —ORo, —SRo, —NHRo, —NRo2, —CORo, —COORo, —NH2, —NO2, —COOH, —CN, hydroxyalkyl, alkylcarbonyloxy, alkoxycarbonyl, alkylcarbonyl and alkylsulfonylamino, with Ro representing an optionally substituted alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heteroaryl, or heterocycloalkyl; and wherein the process uses at least one acidic catalytic system selected from the group consisting of:
(a) a solid acid catalyst, and(b) a mixture of water and CO2.