| 发明名称 |
USE OF GSMTX4 TO REDUCE ISCHEMIA REPERFUSION INJURY |
| 摘要 |
The present invention provides methods for the inhibition of reperfusion injury by treatment with Grammastola spatulata mechanotoxin4 (GsMTx4). The GsMTx4 may be delivered to the ischemic tissue in an individual by any means prior to, during or after ischemia reperfusion injury. |
| 申请公布号 |
US2017072012(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201515122026 |
申请日期 |
2015.03.09 |
| 申请人 |
The research Foundation for The State University of New York |
发明人 |
SACHS Frederick;LI Ji;SUCHYNA Tom;WANG Jinli;GOTTLIEB Philip |
| 分类号 |
A61K38/17;A61L29/16;A61K9/00;A61L31/16 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of reducing ischemic reperfusion injury (IRI) comprising administering to an individual in need of treatment a composition comprising an effective amount of GsMTx4 in a pharmaceutically acceptable carrier at a time from 10 days prior to the TM to 2 days after the IM. |
| 地址 |
Amherst NY US |
