发明名称 PYRAZOLYL-SUBSTITUTED HETEROARYLS AND THEIR USE AS MEDICAMENTS
摘要 The invention relates to new substituted heteroaryls of formula 1 or of formula 1' wherein A is either N or CH, wherein R2 is selected from the group consisting of -C1-3-alkyl, -C1-3-haloalkyl, F, Br, CI, wherein Y is selected from -O- or -CH2-, and wherein R3 is defined as in claim 1, and the pharmaceutically acceptable salts thereof, and the use of these aforementioned compounds for the treatment of diseases such as asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.
申请公布号 WO2017042100(A1) 申请公布日期 2017.03.16
申请号 WO2016EP70729 申请日期 2016.09.02
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 HOFFMANN, Matthias;DAHMANN, Georg;GNAMM, Christian;FANDRICK, Daniel;SCOTT, John;MCCARTHY, Clive
分类号 C07D403/12;A61K31/416;A61K31/437;A61P11/00;A61P11/06;A61P11/08;A61P17/00;C07D231/56;C07D403/14;C07D471/04 主分类号 C07D403/12
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