发明名称 AZOPHENOLS AS ERG ONCOGENE INHIBITORS
摘要 Selective azophenol inhibitors of a wild type or an altered ERG protein expression are described, where the inhibitors represent a compound of Formula (I) or Formula (II), wherein X, X1, X2, X3, X4, X5, R1 through R4 and R9 are as described. An aspect of the present invention relates to a method for treating a disease associated with overexpression of wild type ERG protein, an altered ERG protein, ERG gene transcription or ERG mRNA translation in a subject suffering therefrom, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) or Formula (II)
申请公布号 WO2017044844(A1) 申请公布日期 2017.03.16
申请号 WO2016US51098 申请日期 2016.09.09
申请人 THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. 发明人 DOBI, Albert L.;DALGARD, Clifton;SRIVASTAVA, Shiv
分类号 A61K31/05;A61K31/045;A61K31/15;C07C245/00;C07C245/02;C07C245/04 主分类号 A61K31/05
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