SFRP5-DERIVED PEPTIDE FRAGMENT AND COSMETIC COMPOSITION FOR SKIN WHITENING CONTAINING SAME

摘要

Provided is a peptide fragment derived from secreted frizzled protein 5 (Sfrp5), i.e., a peptide fragment selected from the group consisting of the peptides as set forth in SEQ ID NOs: 1 to 9 and a cosmetic composition for skin-whitening and/or inhibiting skin pigmentation comprising the same as an active ingredient. The peptide fragment inhibits melanin formation in melanocytes, thereby having an inhibitory activity against skin pigmentation. Further provided is a reagent for researching or analyzing the inhibition of Wnt signaling pathways comprising the peptide fragment.

主权项

1. A secreted frizzled protein 5 (Sfrp5)-derived peptide fragment for inhibiting melanin production in melanocytes selected from the group consisting of the peptides as set forth in SEQ ID NOs: 1 to 9.