| 发明名称 |
METHOD FOR DELIVERING A PHARMACEUTICAL COMPOSITION TO PATIENT IN NEED THEREOF |
| 摘要 |
The present disclosure is directed to a method for delivering a pharmaceutical composition to a patient in need thereof, comprising: administering to said patient a pharmaceutical composition in unit dose form comprising naproxen, or pharmaceutically acceptable salt thereof, and esomeprazole, or pharmaceutically acceptable salt thereof. |
| 申请公布号 |
US2017071861(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201615207623 |
申请日期 |
2016.07.12 |
| 申请人 |
POZEN INC. ;HORIZON PHARMA USA, INC. |
发明人 |
AULT Brian;ORLEMANS Everardus;PLACHETKA John R.;SOSTEK Mark |
| 分类号 |
A61K9/24;A61K31/4439;A61K9/00;A61K31/192 |
主分类号 |
A61K9/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for delivering a pharmaceutical composition to a patient in need thereof, comprising: administering to said patient a pharmaceutical composition in unit dose form comprising naproxen, or pharmaceutically acceptable salt thereof, and esomeprazole, or pharmaceutically acceptable salt thereof, wherein said esomeprazole, or pharmaceutically acceptable salt thereof, is released from said unit dose form at a pH of from about 0 or greater to target:
a) a mean % time at which intragastric pH remains at about 4.0 or greater for about a 24 hour period of at least about 41%. |
| 地址 |
Chapel Hill NC US |
