| 发明名称 |
METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY |
| 摘要 |
Disclosed herein are methods for diagnosing a pregnancy related hypertensive disorder or a predisposition to a pregnancy related hypertensive disorder by measuring the level or biological activity of soluble endoglin. Also disclosed herein are methods for treating a pregnancy related hypertensive disorder, such as pre-eclampsia and eclampsia, using compounds that alter soluble endoglin levels or biological activity. |
| 申请公布号 |
US2017072018(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201514729358 |
申请日期 |
2015.06.03 |
| 申请人 |
Beth Israel Deaconess Medical Center, Inc. |
发明人 |
KARUMANCHI S. Ananth;Sukhatme Vikas P. |
| 分类号 |
A61K38/18;A61K39/395;G01N33/74;C07K16/28;C07K14/495;A61K45/06 |
主分类号 |
A61K38/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating or preventing a pregnancy related hypertensive disorder in a subject, said method comprising the step of administering to said subject a compound capable of specifically binding to soluble endoglin, wherein said administering is for a time and in an amount sufficient to treat or prevent said pregnancy related hypertensive disorder in said subject. |
| 地址 |
Boston MA US |
