| 发明名称 |
3-(N,N-DISUBSTITUTED AMINO GROUP) PROPANAMIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN MEDICINE |
| 摘要 |
Provided are a 3-(N,N-disubstituted amino group) propanamide derivative shown in a general formula (I) and a pharmaceutically acceptable salt thereof. Also provided are a 3-(N,N-disubstituted amino group) propanamide compound and a preparation method of a derivative thereof. The general formula (I) has the following structure: R 1, R 2, R 3 and R 4, as described in the specification. Moreover, the compound and a combination thereof can be used as therapeutic agents, and can be used as cholesterylester transfer protein (CETP) inhibitors in particular. |
| 申请公布号 |
WO2017041665(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
WO2016CN97840 |
申请日期 |
2016.09.02 |
| 申请人 |
SHENYANG PHARMACEUTICAL UNIVERSITY |
发明人 |
ZHAO, Dongmei;LIU, Chunchi;XIE, Honglei;SONG, Shuai;BAI, Changlin;MA, Qianqian;HAO, Chenzhou;CHENG, Maosheng |
| 分类号 |
C07D295/185;A61K31/495;A61P9/00;C07C231/02;C07C231/12;C07C237/04;C07C303/40;C07C311/21;C07C311/29;C07D213/75 |
主分类号 |
C07D295/185 |
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