The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.
申请公布号
AU2013232196(C1)
申请公布日期
2017.03.16
申请号
AU20130232196
申请日期
2013.03.13
申请人
Merck Sharp & Dohme Corp.
发明人
Belyk, Kevin M.;Cleator, Edward;Kuo, Shen-Chun;Maligres, Peter Emmanuel;Xiang, Bangping;Yasuda, Nobuyoshi;Yin, Jianguo