| 发明名称 |
SINGLE-CELL ANALYSIS AS A SENSITIVE AND SPECIFIC METHOD FOR EARLY CANCER DETECTION |
| 摘要 |
Certain embodiments are directed to methods of measuring single cell levels of biomarkers associated with prostate cancer. |
| 申请公布号 |
US2017076040(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201515124796 |
申请日期 |
2015.03.14 |
| 申请人 |
Huang Tim Hui-Ming;Chen Chun-Liang;Liu Jeseph;Wang Chiou-Miin;Thompson Ian M.;Lin Chun-Lin |
发明人 |
Huang Tim Hui-Ming;Chen Chun-Liang;Liu Joseph;Wang Chiou-Miin;Thompson Ian M.;Lin Chun-Lin |
| 分类号 |
G06F19/26;C12Q1/68 |
主分类号 |
G06F19/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for stratifying subpopulations of single cells comprising:
(a) measuring single cell gene expression levels for a plurality of target cells isolated from a sample; (b) transforming the single cell gene expression levels to binary form based on bimodal distribution analysis forming a clonally associated numerical pattern (CANP) for each individual target cell; and (c) classifying the sample based on comparing the distribution of CANPs with reference CANPs. |
| 地址 |
San Antonio TX US |
