OXO-DIHYDROIMIDAZO PYRIDINE COMPOUND AND APPLICATIONS THEREOF

摘要

Provided in the present invention are a 2-oxo-1,3-dihydroimidazo pyridine compound as represented by formula (I) and applications of the compound in preparing a medicament for treating various diseases involving Bruton's tyrosine kinase (BTK). Research shows that the compound disclosed is capable of effectively inhibiting the activity of BTK, and thus, by inhibiting BTK, preventing the survival, proliferation, and metastasis of malignant hematologic tumor cells. In addition, inflammation and autoimmune diseases can be mitigated by means of inhibiting BTK. Therefore, the compound of the present invention can be used for treating the various diseases involving BTK, specifically applicable in treating malignant hematologic tumors, inflammation, and autoimmune diseases, and has great application value.