发明名称 |
METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIAL CELLS |
摘要 |
The present invention provides a method for more efficiently producing retinal pigment epithelial cells from pluripotent stem cells. This method for producing retinal pigment epithelial cells comprises the following steps: (1) a first step of culturing pluripotent stem cells for a period not exceeding 30 days, in a medium including an FGF receptor inhibitor and/or a MEK inhibitor; and (2) a second step of forming retinal pigment epithelial cells by culturing the cells obtained in the first step, in the presence of a Nodal signal transduction pathway inhibitor and/or a Wnt signal transduction pathway inhibitor. |
申请公布号 |
WO2017043605(A1) |
申请公布日期 |
2017.03.16 |
申请号 |
WO2016JP76524 |
申请日期 |
2016.09.08 |
申请人 |
SUMITOMO DAINIPPON PHARMA CO., LTD.;HEALIOS K.K. |
发明人 |
ANDO, Satoshi;KURODA, Takao |
分类号 |
C12N5/071;A61K35/30;A61K35/545;A61L27/00;A61P27/02;C12Q1/02 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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