| 发明名称 |
DNA METHYLTRANSFERASES FOR THE TREATMENT AND PREVENTION OF ARTHRITIS |
| 摘要 |
The present disclosure is directed to compositions and methods for treating osteoarthritis comprising increasing the expression of Dnmt3b and/or inhibiting aminobutyrate aminotransferase. |
| 申请公布号 |
US2017071889(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201615265009 |
申请日期 |
2016.09.14 |
| 申请人 |
Washington University |
发明人 |
O'Keefe Regis J.;Shen Jie;McAlinden Audrey |
| 分类号 |
A61K31/197;A61K48/00 |
主分类号 |
A61K31/197 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method to reduce cartilage degradation, the method comprising administering a composition comprising a compound that increases the expression of Dmnt3b and/or a compound that inhibits aminobutyrate aminotransferase. |
| 地址 |
St. Louis MO US |
