| 发明名称 |
A Method of Selecting a Nuclease Target Sequence for Gene Knockout Based on Microhomology |
| 摘要 |
The present invention relates to a method of selecting a nuclease target sequence for gene knockout based on microhomology. |
| 申请公布号 |
US2017076039(A1) |
申请公布日期 |
2017.03.16 |
| 申请号 |
US201515306270 |
申请日期 |
2015.04.24 |
| 申请人 |
INSTITUTE FOR BASIC SCIENCE |
发明人 |
Kim Jin Soo;Bae Sang Su |
| 分类号 |
G06F19/24;G06F19/18 |
主分类号 |
G06F19/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of selecting a nuclease target sequence for gene knockout, comprising:
(a) providing a nuclease target sequence candidate; (b) collecting information of microhomology present in the nuclease target sequence candidate; and (c) predicting frequency of microhomology-associated out-of-frame deletion of the nuclease target sequence candidate based on the information of microhomology collected in step (b). |
| 地址 |
Daejeon KR |
