| 摘要 |
PROBLEM TO BE SOLVED: To provide methods for preventing, treating or delaying heart failure in a mammal.SOLUTION: A method comprises administering a neuregulin 1 protein in an amount of a) about 0.3 μg to about 2.4 μg/kg/day, b) about 6 EU to about 48 EU/kg/day, or c) about 0.04 nmol to about 0.34 nmol/kg/day. The neuregulin 1 protein is a neuregulin 1 &bgr;2 isoform, and intravenously administered 10 minutes to 12 hours per day for one day or multiple days, or 10 hours per day for at least 10 days.SELECTED DRAWING: None |
