| 摘要 |
The present invention aims to provide a biodegradable vascular embolization material that is less likely to coagulate and has an improved flexibility, and whose particle shape is recovered after its passing through a catheter or the like. The present invention provides a biodegradable particle comprising a block copolymer produced by copolymerization of: a biodegradable copolymer having a structure composed of hydroxycarboxylic acid a1, whose homopolymer produced by homopolymerization has a glass transition point of not less than 40°C, and hydroxycarboxylic acid a2, whose homopolymer produced by homopolymerization has a glass transition point of not more than -40°C; a water-soluble polymer comprising a functional group selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group at each of both ends; and a polyvalent compound comprising 2 or more functional groups each selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group; wherein the ratio of the mass of the structure composed of hydroxycarboxylic acid a2 to the mass of the biodegradable copolymer is 30 to 90% by mass. |
