| 发明名称 |
Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA |
| 摘要 |
This invention relates to compounds, compositions, and methods useful for reducing KRAS target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA) agents possessing asymmetric end structures. |
| 申请公布号 |
EP2756845(B1) |
申请公布日期 |
2017.03.15 |
| 申请号 |
EP20140157847 |
申请日期 |
2010.04.05 |
| 申请人 |
Dicerna Pharmaceuticals, Inc. |
发明人 |
Brown, Bob D. |
| 分类号 |
A61K31/713;C12N15/113 |
主分类号 |
A61K31/713 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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