发明名称 |
METHODS OF LINEARLY AMPLIFYING WHOLE GENOME OF A SINGLE CELL |
摘要 |
Embodiments of the disclosure encompass methods of amplifying nucleic acid from one or more cells using MALBAC (multiple annealing and looping-based amplification cycles) primers. In particular embodiments, the nucleic acid is amplified as amplicons in a linear manner. Specific embodiments include the removal or effective destruction of nonlinearly produced amplicons. |
申请公布号 |
EP3140425(A1) |
申请公布日期 |
2017.03.15 |
申请号 |
EP20150788806 |
申请日期 |
2015.05.05 |
申请人 |
Baylor College of Medicine |
发明人 |
ZONG, Chenghang;GUNDRY, Michael;SHENG, Kuanwei |
分类号 |
C12Q1/68;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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