摘要 |
The Present invention provides a useful morpholino nucleic acid derivative for synthesizing a morpholino nucleic acid oligomer.
The present invention provides a compound represented by the following general formula (1) or a salt.
wherein R 1 represents hydrogen, trityl and so on.
R 2 represents amide or imine.
R 3 represents a hydroxy group which may be protected by trialkylsilyl and so on, or a group represented by the following general formula (5).
(wherein X represents O or S. Y represents dialkylamino or alkoxy. Z represents chlorine.) |