发明名称 INHIBITORS OF JMJD2C AS ANTICANCER AGENTS
摘要 The present disclosure provides compounds, pharmaceutical compositions and related methods for the treatment of cancer, e.g., castration-resistant prostate cancer (CRPC). Specifically, the present disclosure provides a series of 8-hydroxyquinoline derivatives which show cytotoxic effects on androgen-independent prostate cancer cells.
申请公布号 EP3137079(A1) 申请公布日期 2017.03.08
申请号 EP20150786844 申请日期 2015.04.21
申请人 The J. David Gladstone Institutes 发明人 XIE, Min;DING, Sheng
分类号 A61K31/4709;C07D215/24 主分类号 A61K31/4709
代理机构 代理人
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