| 发明名称 | Methods and pharmaceutical compositions for the treatment of an ocular disease in a subject | ||
| 摘要 | Provided herein is a method for treating an ocular disease in a subject comprising the steps consisting of i) delivering a pharmaceutical composition formulated with a therapeutic nucleic acid of interest into the suprachoroidal space of the diseased eye and ii) exposing the region where the pharmaceutical composition was delivered to an electrical field. | ||
| 申请公布号 | US9586045(B2) | 申请公布日期 | 2017.03.07 |
| 申请号 | US201214238607 | 申请日期 | 2012.08.14 |
| 申请人 | Institut Nationale de la Santé et de la Recherche Médicale | 发明人 | Behar-Cohen Francine;Touchard Elodie;Berdugo Polak Marianne |
| 分类号 | C12N13/00;A61K48/00;A61N1/32;A61K38/18;A61K9/00 | 主分类号 | C12N13/00 |
| 代理机构 | Whitham, Curtis & Cook, P.C. | 代理人 | Whitham, Curtis & Cook, P.C. |
| 主权项 | 1. A method for treating an ocular disease in a subject comprising the steps of i) delivering a pharmaceutical composition formulated with a therapeutic nucleic acid of interest into the suprachoroidal space of the diseased eye and ii) exposing the region where the pharmaceutical composition was delivered to an electrical field, wherein a field intensity of the electrical field is superior or equal to 15 volts and is inferior to 60 volts. | ||
| 地址 | Paris FR | ||