| 主权项 |
1. A non-drug-eluting ureteral stent, comprising:
an elongate portion having an inner surface defining a lumen and an outer surface configured to contact a portion of a body, the elongate portion having a plurality of side ports defined therein, a side port of the plurality of side ports defining an opening from the outer surface to the lumen, the elongate portion having a first retention portion configured to be placed within a bladder of a patient and a second retention portion configured to be placed within a kidney of the patient, the first retention portion being disposed in a first orientation with respect to a longitudinal axis of a medial portion of the elongate portion, the second retention portion being disposed in a second orientation with respect to the longitudinal axis, the second orientation being different than the first orientation, the second retention portion being constructed from a first material and a second material combined with the first material to form a composite of the first material and the second material, the first retention portion being constructed from the first material and being devoid of the second material, a concentration of the second material in the composite of the first material and the second material varying along a length of the elongate portion, the first material being formulated to be insoluble in a bodily fluid, the second material being formulated to be soluble in the bodily fluid, the first material having a first hardness, and the second material has a second hardness that is greater than the first hardness, the first material including a radiopaque material, the second material, when in contact with the bodily fluid, will dissolve in one hour, such that a hardness of the second retention portion decreases while a size and a shape of the second retention portion remain unchanged, and a dissolution rate of the second material as a function of a time in contact with the bodily fluid is constant. |
