发明名称 |
PROCESS FOR THE PREPARATION OF NEBIVOLOL |
摘要 |
The present invention relates to a novel process for the synthesis of Nebivolol product represented in Scheme (1), comprised of a reduced number of high-yield steps, and characterized by the kinetic resolution of the two epoxide pairs diastereoisomeric therebetween (mixture 1), allowing to avoid complex chromatographic separations. |
申请公布号 |
CA2786833(C) |
申请公布日期 |
2017.03.07 |
申请号 |
CA20112786833 |
申请日期 |
2011.02.09 |
申请人 |
MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A. |
发明人 |
BARTOLI, SANDRA;CIPOLLONE, AMALIA;FATTORI, DANIELA |
分类号 |
C07D311/58 |
主分类号 |
C07D311/58 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|