Membrane biosensor having multi-hole film attached thereto and method for measuring immunological reaction or enzymatic reaction using the same

摘要

The present invention relates to a membrane sensor having a multi-hole film attached thereto and a method for measuring immunological reactions or enzymatic reactions using the same. More specifically, the present invention relates to a membrane sensor in which a multi-hole film is joined to the top of a membrane on which receptors are immobilized, and a method for measuring immunological reactions or enzymatic reactions using the same. The present invention makes it possible to adjust the sensitivity of membrane biosensors by adjusting the hole size in the multi-hole film and so makes it possible to measure analytes with a high degree of sensitivity using just a small amount of sample, and makes it possible to simultaneously measure diverse types of analyte by attaching various types of receptor on the membrane sensor.

主权项

1. A membrane biosensor comprising:
a film comprising a plurality of holes, wherein the film is attached to a top of a membrane, and each hole of the plurality of holes is separated from adjacent holes of the plurality of holes; receptors immobilized at locations on the membrane; and a conjugate pad on the film, wherein a location of each receptor of the receptors is defined by a corresponding hole of the plurality of holes, wherein the holes have a size ranging from 10 to 5000 μm.