| 发明名称 | Method of producing chemical product with continuous fermentation and filtering | ||
| 摘要 | The invention provides a method of producing a chemical product through continuous fermentation which includes filtering a culture of a microorganism or cultured cells with a separation membrane to recover a product from a filtrate and simultaneously retaining a nonfiltered fluid in, or refluxing it to, the culture, and adding fermentation materials to the culture, wherein a porous membrane having an average pore size of 0.01 μm or more to less than 1 μm is used as the separation membrane and the filtration is conducted with a transmembrane pressure difference in the range of 0.1 to 20 kPa. According to this method, the fermentation productivity of the chemical product can be largely elevated at high stability and a low cost. | ||
| 申请公布号 | US9587253(B2) | 申请公布日期 | 2017.03.07 |
| 申请号 | US200712280197 | 申请日期 | 2007.02.16 |
| 申请人 | Toray Industries, Inc. | 发明人 | Sawai Hideki;Yamada Katsushige;Mimitsuka Takashi;Sawai Kenji;Yonehara Tetsu;Ito Yohito;Henmi Masahiro |
| 分类号 | C12P13/04;C12P7/06;C12M1/00;C12M1/34;C12P7/18;C12P7/46;C12P7/50;C12P7/56;C12P13/00;C12P13/08;C12P19/30 | 主分类号 | C12P13/04 |
| 代理机构 | DLA Piper LLP (US) | 代理人 | DLA Piper LLP (US) |
| 主权项 | 1. A method of producing a chemical product through continuous fermentation which includes filtering a culture of a yeast or bacteria with a separation membrane to recover a product from a filtrate and simultaneously retaining a nonfiltered fluid in, or refluxing it to, the culture, and adding fermentation materials to the culture, wherein a porous membrane having an average pore size of 0.01 μm or more to less than 1 μm is a polyvinylidene fluoride hollow fiber membrane used as the separation membrane and the filtration is conducted with a transmembrane pressure difference in the range of 0.1 to 20 kPa. | ||
| 地址 | JP | ||